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Company Name: Anhui Royal Chemical Co., Ltd.
Tel: +86-025-86736275
Email: [email protected]
Products Intro: Product Name:Tert-Butyldimethylsilyl chloride
CAS:18162-48-6
Purity:99.00% Package:25kg/drum;200kg/drum Remarks:pharmaceutical intermediates; blocking agent;
Company Name: Shanghai Yingrui Biopharma Co., Ltd.
Tel: +86-21-33585366 E-mail：[email protected]
Email: [email protected]
Products Intro: Product Name:tert-Butyldimethylsilyl chloride
CAS:18162-48-6
Purity:99% Package:100g;500g;1kg;25kg...
Company Name: Capot Chemical Co.,Ltd.
Tel: +86 (0)571-855 867 18
Email: [email protected]
Products Intro: Product Name:Tert-Butyl dimethyl silyl chloride
CAS:18162-48-6
Purity:98%(Min,GC) Package:100g;1kg;5kg,10kg,25kg,50kg
Company Name: Shenzhen Sendi Biotechnology Co.Ltd.
Tel: 0755-23311925 18102838259
Email: [email protected]
Products Intro: Product Name:tert-Butyldimethylsilyl chloride
CAS:18162-48-6
Purity:99% Package:452/KG
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Email: [email protected]
Products Intro: Product Name:t-BUTYLDIMETHYLCHLOROSILANE
CAS:18162-48-6
Purity:99% Package:100g,500g,1KG,10KG,100KG Remarks:Low M.W.Organic Silanes Professor

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tert-Butyldimethylsilyl chloride Chemical Properties
Melting point 86-89 °C
Boiling point 125 °C(lit.)
density 0.87 g/mL at 20 °C(lit.)
refractive index n20/D 1.46
Fp 73 °F
storage temp. Store at 5°C
form Liquid
color Clear colorless
Specific Gravity1.225
Water Solubility Soluble in chloroform and ethyl acetate. Insoluble in water.
Sensitive Moisture Sensitive
BRN 505999
InChIKeyBCNZYOJHNLTNEZ-UHFFFAOYSA-N
CAS DataBase Reference18162-48-6(CAS DataBase Reference)
NIST Chemistry ReferenceSilane, chloro(1,1-dimethylethyl)dimethyl-(18162-48-6)
EPA Substance Registry SystemSilane, chloro(1,1-dimethylethyl)dimethyl- (18162-48-6)
Safety Information
Hazard Codes C,F,T,Xn
Risk Statements 22-35-40-34-10-19-11-67-65-63-48/20-20/21/22-45-23/24/25-37-36/37/38
Safety Statements 26-36/37/39-46-62-45-25-16-28-27-33-29-53-36/37
RIDADR UN 2925 4.1/PG 2
WGK Germany 2
RTECS VV2000000
F 10-21
Hazard Note Flammable/Corrosive/Moisture Sensitive
TSCA Yes
HazardClass 4.1
PackingGroup III
HS Code 29310095
MSDS Information
ProviderLanguage
TBDMCS English
SigmaAldrich English
ACROS English
ALFA English
tert-Butyldimethylsilyl chloride Usage And Synthesis
IntroductionTriethylchlorosilane is a clear, colourless to yellowish, pungent smelling, caustic and flammable liquid. It can be dissolved in non-protonating solvents without decomposition.
It may be used as silylating agent for dervatization of primary and secondary alcohols etc.. Also it may be used to protect allylic esters as silylketene acetal which is ore stable but less volatile derivates than trimethylchlorosilane.
Chemical PropertiesWhite solid
UsesUsed to protect alcohols during organic synthesis.
DefinitionChEBI: A silyl chloride consisting of a central silicon atom covalently bound to one chloro, one tert-butyl and two methyl groups. tert-Butyldimethylsilyl chloride is a derivatisation agent used in gas chromatography/mass spectrometry ap lications.
HazardModerately toxic.
Purification MethodsFractionally distil it at atmospheric pressure. [Sommer & Tyler J Am Chem Soc 76 1030 1954, Corey & Venkateswarlu J Am Chem Soc 94 6190 1972, Beilstein 4 IV 4076.]
Tag:tert-Butyldimethylsilyl chloride(18162-48-6) Related Product Information
2-Chloro-2-methylpropane Triethylsilane Fattyalkyl dimethyl amine Pivaloyl chloride Chloro(chloromethyl)dimethylsilane Ammonium chloride Potassium chloride Dimethyl phthalate Dimethyl sulfate DI-TERT-BUTYLDICHLOROSILANE Dimethyl sulfide Dimethyl sulfoxide ETHANE Calcium chloride Choline chloride CHLORIDE STANDARD Dimethyl carbonate Dichlorodimethylsilane