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中国福彩网积分兑换:DICALCIUM PHOSPHATE DIHYDRATE

DICALCIUM PHOSPHATE DIHYDRATE
DICALCIUM PHOSPHATE DIHYDRATE structure
CAS No.
7789-77-7
Chemical Name:
DICALCIUM PHOSPHATE DIHYDRATE
Synonyms
DiTab;Di-tab;Bekapress D 2;CALCIUM PHOSPH;DICALCIUM PHOSPHAT;BicalciuM phosphate;dicalciurn phosphate;Calcium phosphate di;calcium phosphate,secondary;Calciumhydrogenphosphate,dih
CBNumber:
CB9439551
Molecular Formula:
CaH5O6P
Formula Weight:
172.09
MOL File:
7789-77-7.mol

DICALCIUM PHOSPHATE DIHYDRATE Properties

Melting point:
109°C -H₂O
Density 
2.31
solubility 
Practically insoluble in water and in ethanol (96 per cent). It dissolves in dilute hydrochloric acid and in dilute nitric acid.
form 
Solid
color 
White to almost white
Water Solubility 
Slightly soluble in water. Soluble in dilute hydrochloric, nitric, and acetic acid. Insoluble in alcohol
Stability:
Stable. Incompatible with acids.
InChIKey
XAAHAAMILDNBPS-UHFFFAOYSA-L
CAS DataBase Reference
7789-77-7(CAS DataBase Reference)
EWG's Food Scores
1
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  1
TSCA  Yes
HS Code  28352590
NFPA 704
0
1 0

DICALCIUM PHOSPHATE DIHYDRATE price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 307653 Calcium hydrogenphosphate dihydrate 98% 7789-77-7 500g $65.1 2019-12-02 Buy
Sigma-Aldrich 04231 Calcium phosphate dibasic dihydrate puriss., meets analytical specification of Ph. Eur., BP, USP, 98-102.5% 7789-77-7 1kg $74.2 2019-12-02 Buy
Alfa Aesar 040233 Calcium hydrogen phosphate dihydrate, 98% min 7789-77-7 1kg $78.5 2019-12-02 Buy
Alfa Aesar 040233 Calcium hydrogen phosphate dihydrate, 98% min 7789-77-7 5kg $225 2019-12-02 Buy

DICALCIUM PHOSPHATE DIHYDRATE Chemical Properties,Uses,Production

Chemical Properties

white crystalline solid

Chemical Properties

Dibasic calcium phosphate dihydrate is a white, odorless, tasteless powder or crystalline solid. It occurs as monoclinic crystals.

Uses

Replenisher (calcium); pharmaceutic aid (tablet base).

Uses

Dicalcium Phosphate, Dihydrate is a source of calcium and phosphorus that also functions as a dough conditioner and bleaching agent. It functions as a dough conditioner in bakery products, as a bleaching agent in flour, as a source of calcium and phosphorus in cereal products, and as a source of calcium for alginate gels. It contains approximately 23% calcium. It is practically insoluble in water. It is also termed dibasic calcium phosphate, dihydrate and calcium phosphate dibasic, hydrous. It is used in dessert gels, baked goods, cereals, and breakfast cereals.

Uses

Dicalcium phosphate dihydrate is only slightly soluble at ordinary temperatures of mixing and holding doughs and batters. As a result, it does not release acidity for reaction with soda until late in the baking stage, when the temperature reaches 135 to 140°F. Since DCP·2H20 does not begin to react below 135°F, and the interior structure of a baked product begins to firm at about 160°F, a product that bakes rapidly may not provide sufficient time for complete release of all the C02. DCP·2H2 0, therefore, cannot be used in biscuits, pancakes or any baked product that is completely baked in less than 20 min.
Dicalcium phosphate dihydrate is seldom used by itself in leavening systems but is usually combined with fasterreacting acidic phosphates. Its major applications are in cake mixes, frozen bread doughs, and other products requiring a half hour or more to complete baking. It has a low neutralizing value, and therefore more DCP·2H20 is required to neutralize a given amount of soda than for other phosphate-leavening acids.

Production Methods

Calcium phosphates are usually manufactured by reacting very pure phosphoric acid with calcium hydroxide, Ca(OH)2 obtained from limestone, in stoichiometric ratio in aqueous suspension followed by drying at a temperature that will allow the correct hydration state to be achieved. After drying, the coarse-grade material is obtained by means of a classification unit; the fine particle-size material is obtained by milling.

brand name

CalStar (FMC); D.C.P. (Parke-Davis).

Pharmaceutical Applications

Dibasic calcium phosphate dihydrate is widely used in tablet formulations both as an excipient and as a source of calcium and phosphorus in nutritional supplements. It is one of the more widely used materials, particularly in the nutritional/health food sectors. It is also used in pharmaceutical products because of its compaction properties, and the good flow properties of the coarsegrade material. The predominant deformation mechanism of dibasic calcium phosphate coarse-grade is brittle fracture and this reduces the strain-rate sensitivity of the material, thus allowing easier transition from the laboratory to production scale. However, dibasic calcium phosphate dihydrate is abrasive and a lubricant is required for tableting, for example about 1% w/w of magnesium stearate or about 1% w/w of sodium stearyl fumarate is commonly used.
Two main particle-size grades of dibasic calcium phosphate dihydrate are used in the pharmaceutical industry. The milled material is typically used in wet-granulated, roller-compacted or slugged formulations. The ‘unmilled’ or coarse-grade material is typically used in direct-compression formulations.
Dibasic calcium phosphate dihydrate is nonhygroscopic and stable at room temperature. However, under certain conditions of temperature and humidity, it can lose water of crystallization below 1008℃. This has implications for certain types of packaging and aqueous film coating since the loss of water of crystallization appears to be initiated by high humidity and by implication high moisture vapor concentrations in the vicinity of the dibasic calcium phosphate dihydrate particles.
Dibasic calcium phosphate dihydrate is also used in toothpaste and dentifrice formulations for its abrasive properties.

Safety

Dibasic calcium phosphate dihydrate is widely used in oral pharmaceutical products, food products, and toothpastes, and is generally regarded as a nontoxic and nonirritant material. However, oral ingestion of large quantities may cause abdominal discomfort.

storage

Dibasic calcium phosphate dihydrate is a nonhygroscopic, relatively stable material. However, under certain conditions the dihydrate can lose water of crystallization. This has implications for both storage of the bulk material and coating and packaging of tablets containing dibasic calcium phosphate dihydrate.
The bulk material should be stored in a well-closed container in a cool, dry place.

Purification Methods

Crystallise it from a near-saturated solution in 50% aqueous reagent grade phosphoric acid at 100o by filtering through fritted glass and cooling to room temperature. The crystals are filtered off, and this process is repeated three times using fresh acid. For the final crystallisation the solution is cooled slowly with constant stirring to give thin plate crystals that are filtered off on a fritted glass funnel, washed free of acid with anhydrous acetone and dry in a vacuum desiccator [Egan et al.J Am Chem Soc 78 1811 1956].

Incompatibilities

Dibasic calcium phosphate dihydrate should not be used to formulate tetracycline antibiotics. Dibasic calcium phosphate dihydrate has been reported to be incompatible with indomethacin, aspirin, aspartame, ampicillin, cephalexin, and erythromycin. The surface of dibasic calcium phosphate dihydrate is alkaline and consequently it should not be used with drugs that are sensitive to alkaline pH.

Regulatory Status

GRAS listed. Accepted as a food additive in Europe. Included in the FDA Inactive Ingredients Database (oral capsules and tablets). Included in nonparenteral medicines licensed in Europe. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

DICALCIUM PHOSPHATE DIHYDRATE Preparation Products And Raw materials

Raw materials

Preparation Products


DICALCIUM PHOSPHATE DIHYDRATE Suppliers

Global( 185)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
[email protected] CHINA 21816 58
Jiangsu Kolod Food Ingredients Co.,Ltd.
+86-518-85110578 18805133257
+86-518-85110578 [email protected] CHINA 100 60
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 [email protected] CHINA 22631 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 [email protected] China 2368 55
Hebei Chisure Biotechnology Co., Ltd.
+8613292890173
0311 66567340 [email protected] CHINA 1010 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038
[email protected] CHINA 3623 58
Hebei Ruishun Trade Co.,LTD
17052563120
[email protected] CHINA 302 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 [email protected];[email protected];[email protected];[email protected] CHINA 23979 58
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093 [email protected] CHINA 9388 58
Hebei Guanlang Biotechnology Co., Ltd.
+8619930501651
whatsapp: +8619930501651 [email protected] CHINA 2404 58

View Lastest Price from DICALCIUM PHOSPHATE DIHYDRATE manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-04-02 Calcium hydrogenphosphate dihydrate Manufacturer; In stock GMP Factory
7789-77-7
US $1.00 / KG 1KG High quality manufacturer TOP 3 largest production factory in China Chemwill Asia Co.,Ltd.
2018-09-12 Calcium hydrophosphate dihydrate
7789-77-7
US $1.00 / G 100G 99.9% 50000tons Hebei Ruishun Trade Co.,Ltd
2020-01-08 DICALCIUM PHOSPHATE DIHYDRATE
7789-77-7
US $9.80 / KG 1g ≥99% 100kg Career Henan Chemical Co

DICALCIUM PHOSPHATE DIHYDRATE Spectrum


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